IDENTIFICATION OF THE ABCC4, IER3, AND CBFA2T2 CANDIDATE GENES FOR RESISTANCE TO PARATUBERCULOSIS FROM SEQUENCE-BASED GWAS IN HOLSTEIN AND NORMANDE DAIRY CATTLE

Abstract Background Bovine paratuberculosis is a contagious disease, caused by Mycobacterium avium subsp.paratuberculosis (MAP), with adverse effects on animal welfare and serious economic consequences.Published results on host genetic resistance to MAP are inconsistent, mainly because of difficulties in characterizing the infection status of cows.